Principles of neural science

 
 

  作者: Kandel, Eric R.  
版次: 5
出版年: 2013
出版社: McGraw-Hill Medical
ISBN: 9780071390118
索书号: R338/KER/=5(Y0)
页数: 1709
借出次数: 1
   
 
   
  图书描述:  
 

900 full-color illustrations

Deciphering the link between the human brain and behavior has always been one of the most intriguing—and often challenging—aspects of scientific endeavor. The sequencing of the human genome, and advances in molecular biology, have illuminated the pathogenesis of many neurological diseases and have propelled our knowledge of how the brain controls behavior.

To grasp the wider implications of these developments and gain a fundamental understanding of this dynamic, fast-moving field, Principles of Neuroscience stands alone as the most authoritative and indispensible resource of its kind.

In this classic text, prominent researchers in the field expertly survey the entire spectrum of neural science, giving an up-to-date, unparalleled view of the discipline for anyone who studies brain and mind. Here, in one remarkable volume, is the current state of neural science knowledge—ranging from molecules and cells, to anatomic structures and systems, to the senses and cognitive functions—all supported by more than 900 precise, full-color illustrations. In addition to clarifying complex topics, the book also benefits from a cohesive organization, beginning with an insightful overview of the interrelationships between the brain, nervous system, genes, and behavior. Principles of Neural Science then proceeds with an in-depth examination of the molecular and cellular biology of nerve cells, synaptic transmission, and the neural basis of cognition. The remaining sections illuminate how cells, molecules, and systems give us sight, hearing, touch, movement, thought, learning, memories, and emotions.

The new fifth edition of Principles of Neural Science is thoroughly updated to reflect the tremendous amount of research, and the very latest clinical perspectives, that have significantly transformed the field within the last decade.

Ultimately, Principles of Neural Science affirms that all behavior is an expression of neural activity, and that the future of clinical neurology and psychiatry hinges on the progress of neural science. Far exceeding the scope and scholarship of similar texts, this unmatched guide offers a commanding, scientifically rigorous perspective on the molecular mechanisms of neural function and disease—one that you’ll continually rely on to advance your comprehension of brain, mind, and behavior.

FEATURES

The cornerstone reference in the field of neuroscience that explains how the nerves, brain, and mind function
Clear emphasis on how behavior can be examined through the electrical activity of both individual neurons and systems of nerve cells
Current focus on molecular biology as a tool for probing the pathogenesis of many neurological diseases, including muscular dystrophy, Huntington disease, and certain forms of Alzheimer’s disease
More than 900 engaging full-color illustrations—including line drawings, radiographs, micrographs, and medical photographs clarify often-complex neuroscience concepts
Outstanding section on the development and emergence of behavior, including important coverage of brain damage repair, the sexual differentiation of the nervous system, and the aging brain
NEW! More detailed discussions of cognitive and behavioral functions, and an expanded review of cognitive processes
NEW! A focus on the increasing importance of computational neural science, which enhances our ability to record the brain’s electrical activity and study cognitive processes more directly
NEW! Chapter-opening Key Concepts provide a convenient, study-enhancing introduction to the material covered in each chapter
Selected Readings and full reference citations at the close of each chapter facilitate further study and research
Helpful appendices highlight basic circuit theory; the neurological examination of the patient; circulation of the brain; the blood-brain barrier, choroid plexus, and cerebrospinal fluid; neural networks; and theoretical approaches to neuroscience

 

目录:

Preface
Acknowledgments
Contributors
Part I
Overall Perspective
1 The Brain and Behavior
2 Nerve Cells, Neural Circuitry, and Behavior
3 Genes and Behavior
Part II
Cell and Molecular Biology of the Neuron
4 The Cells of the Nervous System
5 Ion Channels
6 Membrane Potential and the Passive Electrical Properties of the Neuron
7 Propagated Signaling: The Action Potential
Part III
Synaptic Transmission
8 Overview of Synaptic Transmission
9 Signaling at the Nerve-Muscle Synapse: Directly Gated Transmission
10 Synaptic Integration in the Central Nervous System
11 Modulation of Synaptic Transmission: Second Messengers
12 Transmitter Release
13 Neurotransmitters
14 Diseases of the Nerve and Motor Unit
Part IV
The Neural Basis of Cognition
15 The Organization of the Central Nervous System
16 The Functional Organization of Perception and Movement
17 From Nerve Cells to Cognition: The Internal Representations of Space and Action
18 The Organization of Cognition
19 Cognitive Functions of the Premotor Systems
20 Functional Imaging of Cognition
Part V
Perception
21 Sensory Coding
22 The Somatosensory System: Receptors and Central Pathways
23 Touch
24 Pain
25 The Constructive Nature of Visual Processing
26 Low-Level Visual Processing: The Retina
27 Intermediate-Level Visual Processing and Visual Primitives
28 High-Level Visual Processing: Cognitive Influences
29 Visual Processing and Action
30 The Inner Ear
31 The Auditory Central Nervous System
32 Smell and Taste: The Chemical Senses
Part VI
Movement
33 The Organization and Planning of Movement
34 The Motor Unit and Muscle Action
35 Spinal Reflexes
36 Locomotion
37 Voluntary Movement: The Primary Motor Cortex
38 Voluntary Movement: The Parietal and Premotor Cortex
39 The Control of Gaze
40 The Vestibular System
41 Posture
42 The Cerebellum
43 The Basal Ganglia
44 Genetic Mechanisms in Degenerative Diseases of the Nervous System
Part VII
The Unconscious and Conscious Processing of Neural Information
45 The Sensory, Motor, and Reflex Functions of the Brain Stem
46 The Modulatory Functions of the Brain Stem
47 The Autonomic Motor System and the Hypothalamus
48 Emotions and Feelings
49 Homeostasis, Motivation, and Addictive States
50 Seizures and Epilepsy
51 Sleep and Dreaming
Part VIII
Development and the Emergence of Behavior
52 Patterning the Nervous System
53 Differentiation and Survival of Nerve Cells
54 The Growth and Guidance of Axons
55 Formation and Elimination of Synapses
56 Experience and the Refinement of Synaptic Connections
57 Repairing the Damaged Brain
58 Sexual Differentiation of the Nervous System
59 The Aging Brain
Part IX
Language, Thought, Affect, and Learning
60 Language
61 Disorders of Conscious and Unconscious Mental Processes
62 Disorders of Thought and Volition: Schizophrenia
63 Disorders of Mood and Anxiety
64 Autism and Other Neurodevelopmental Disorders Affecting Cognition
65 Learning and Memory
66 Cellular Mechanisms of Implicit Memory Storage and the Biological Basis of Individuality
67 Pre-Frontal Cortex, Hippocampus, and the Biology of Explicit Memory Storage
Appendices
A Review of Basic Circuit Theory
B The Neurological Examination of the Patient
C Circulation of the Brain
D The Blood–Brain Barrier, Choroid Plexus, and Cerebrospinal Fluid
E Neural Networks
F Theoretical Approaches to Neuroscience: Examples from Single Neurons to Networks
Index

 
 

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